AstraZeneca suffers setback in COVID-19 treatment development

AstraZeneca treatment unsuccessful at preventing symptomatic COVID-19

Previously, NACI had said AstraZeneca recipients could choose whether to get a second dose of the same vaccine, or an mRNA vaccine.

However, the panel notes, those ages 50-59 who have already received a first dose of AstraZeneca and did not experience abnormal side effects are still advised to receive the second dose.

There are 14 million doses of Pfizer-BioNTech and Moderna being delivered this week and next, including a donation of one million doses of Moderna's COVID-19 vaccine from the United States that arrived in Canada on Thursday. -Gen. Krista Brodie, said there are still approximately 600,000 doses of AstraZeneca unused in Canada and it will be up to the provinces and territories to determine how best to use them. Many have continued using it for booster shots.

"AstraZeneca remains a very effective vaccine, the benefit of AstraZeneca in the over 60s remains much higher than the risk of this particularly rare, but sometimes serious syndrome", he said.

As of June 5, 2.1 million Canadians had received one dose of AstraZeneca, and 15,186 had received two doses.

The rate of thrombosis with thrombocytopenia syndrome (TTS) after a second dose of the AstraZeneca vaccine is significantly lower than after first doses, evidence from the United Kingdom has shown.

Under 60s are now recommended to get the Pfizer vaccine.

But a recent study by the U.K. Coronavirus Immunology Consortium and the University of Birmingham found that the AstraZeneca vaccine may actually induce a stronger cellular immune response than the Pfizer shot.

Australia's Chief Medical Officer Paul Kelly said the new cases had "changed the rate" for those between 50 and 59, changing the risk profile more in line with those under 50.

"Discussions regarding next steps with the U.S. government are ongoing", the company said.

That 9.5 million figure includes the one million doses that were donated to Canada by the USA this morning. "Vaccine supply is rapidly increasing".

Brodie said Pfizer is still planning to meet its commitment to send nine million doses to Canada next month but the government now expects "a lower allocation in early July and a larger allocation later in July to offset".

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