Covid-19 infects neurons, damages brain tissues, study finds

In the future, scientists feel Covid will resemble the common cold-causing virus

Many of these animals circulate in animal populations like bats and have the potential to "jump" into the human population, just like SARS-CoV-2.

SARS-CoV-2 is an enveloped positive-stranded RNA virus that consists of four structural proteins including spike glycoprotein, envelope protein, membrane protein, and nucleocapsid protein.

The four common cold-causing coronaviruses have been circulating in humans for a long time and nearly everyone is infected at a young age - younger than measles before a vaccine was available.

Older individuals could still become infected, but their childhood infections would provide immune protection against severe disease, according to the researchers.

"So really, the name of the game is getting everyone exposed for the first time to the vaccine as quickly as possible", Jennie Lavine, a postdoctoral fellow at Emory University in Atlanta, who led the study, told the New York Times.

These new kit products include SARS-CoV-2 inhibitor screening kits, antibody titer serologic assay kits, antigen detection kit, and antigen pre-coated plates.

The US Food and Drug Administration (FDA; Silver Spring, MD, USA) has alerted clinical laboratory staff and health care providers that it is monitoring the potential impact of viral mutations, including an emerging variant from the United Kingdom known as the B.1.1.7 variant, on authorized SARS-CoV-2 molecular tests.

"The FDA will continue to monitor SARS-CoV-2 genetic viral variants to ensure authorized tests continue to provide accurate results for patients", Dr. Stephen Hahn, FDA Commissioner, said.

"We are in uncharted territory, but a key take-home message from the study is that immunological indicators suggest that fatality rates and the critical need for broad-scale vaccination may wane in the near term, so maximum effort should be on weathering this virgin pandemic enroute to endemicity", said Ottar Bjornstad, Distinguished Professor of Entomology and Biology and J. Lloyd & Dorothy Foehr Huck Chair of Epidemiology, Penn State.

The scientists said that nearly everyone catches one of the endemic cold coronaviruses during childhood, often before the age of 5, which gives partial immunity to adults who become reinfected later in life.

The model predicts that the infection fatality ratio for SARS-CoV-2 may fall below that of seasonal influenza (0.1 percent), once an endemic steady-state is reached.

One of the biggest puzzles to haunt covid-19 vaccine research labs was how long the immunity of patients who survived SARS-CoV-2 would last.

This observation indicates that exposure to these common cold viruses does not necessarily eliminate the chance for future infection, but that subsequent infections become less likely to cause serious illness. The answer has now come: it can last eight months or more.



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