Stroke, Confusion: COVID-19 Often Impacts the Brain, Study Shows

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The researchers believe that patients with COVID-19 should be evaluated early for acute neurological changes.

They caution that the "rates of neurological and psychiatric complications of COVID-19 can not be extrapolated to mildly affected patients or patients with asymptomatic infection, especially those in the community".

This data represents an important snapshot of the brain-related complications of COVID-19 in hospitalised patients.

Co-author Dr Benedict Michael, from Liverpool University, said: 'Whilst an altered mental state was being reported by some clinicians, we were surprised to identify quite so many cases, particularly in younger patients, and by the breadth of clinical syndromes ranging from brain inflammation (encephalitis) through to psychosis and catatonia.

A small study found a correlation between brain complications and severe cases of COVID-19, raising concerns about the disease's impact in some patients.

They said these portals were hosted by professional bodies representing specialists in neurology, stroke, psychiatry and intensive care.

Data was collected between April 2 and April 26 - when the disease was spreading exponentially in the UK.

Now researchers from University College London have found that some hospitalised COVID -19 patients show signs of confusion, changes in behaviour and other brain complications, including stroke, psychosis and dementia-like syndrome. World Health Organization has also busted some myths surrounding coronavirus. The study is based on the observations of physicians, and therefore a clear picture will be provided by further studies, experts say.

According to Pett, similar studies conducted on a larger scale can help understand the "frequency of these brain complications, who's most at risk of getting them, and ultimately how best to treat".

Full clinical details were provided for 125 patients using multiple testing methods, including chest x-rays and CT scans as well as PRC testing at 6 and 114 people, respectively.

'It reminds us that Covid-19 is more than a respiratory infection and that we need to consider its link to variety of other illnesses.

A study of 153 patients treated in United Kingdom hospitals during the acute phase of the COVID-19 pandemic describes a range of neurological and psychiatric complications that may be linked to the disease, including stroke and an altered mental state such as brain inflammation, psychosis and dementia-like symptoms. Of these, most were in patients over 60, and most were caused by a blood clot in the brain, known as an ischaemic stroke. Most of the patients who had a stroke were older than 60 years of age.

Age information was available for 37 of the 39 patients with an altered mental state.

Of those, nine had unspecified brain dysfunction (encephalopathy), seven had inflammation of the brain (encephalitis), and 23 were diagnosed with psychiatric conditions, the researchers said. Long-term follow-up studies to assess duration and severity of these complications are needed. Ten of the patients with an altered mental state developed psychosis-disruptions that make it hard for an individual to determine what is real and what isn't. Seven patients had signs of a mood disorder, including depression and anxiety (7/23). While stroke mostly occurred in older patients, those who experience an altered mental state were seen across all ages.

The researchers noted that some of these could have existed before the patients contracted Covid-19, but remained previously undiagnosed.



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