Danny Care and Jonathan Joseph come in for England against Wales

Rob Evans

Eddie Jones trained his sights on Alun Wyn Jones and Rhys Patchell as he launched his fiercest verbal assault yet on "cocky" Wales before the NatWest Six Nations showdown at Twickenham tomorrow.

Care will become England's most capped scrum half (78), moving past 2003 Rugby World Cup victor Matt Dawson.

"It's a massive honour to overtake Matt, who was a hero of mine growing up", said Harlequins No.9 Care.

"He texted me last weekend to say well done when I equalled his record, but he said he'd save the soppy one for Saturday".

Wales brushed aside any injury concerns of their own with a superb performance in their one-sided 34-7 win at home to Scotland.

They've got to get the ball wide and Patchell hasn't played much Test match rugby. "You've still got to respect the integrity of the referee".

England's hardest fixture of the tournament is already shaping up to be their trip to France in the penultimate round but they are favourites to defend their title and are expected to beat a transitional Wales side, having won 63-0 in Cardiff previous year.

"I can speak for the whole team when I say we are excited to get back to our turf and rip into what is going to be a huge game". "You can choose your friends but you can't choose your family, I'll have to have a chat with Uncle Eddie after the game". He led the 2013 Lions to a 2-1 series win in Australia and past year his Lions drew the series 1-all in New Zealand after the final Test ended in a 12-all draw.

The Wales skipper also said he took no offence at being called "out of order" by England's supremo.

"It's been brilliant and one hell of a journey and I want to get 78 more if I can because I love playing for England".

"I have a slightly better haircut, I'm a bit wiser, not as rash, been part of big games and experienced highs and lows which has moulded me into the player I am now", he added. The players are bigger, faster, stronger.

"I can remember 18 or 24 months ago someone at the Rugby Football Union, whose name I don't recollect at the moment, coming in and saying 'you play Italy on Sunday and Wales on Saturday, it that ok?'".

That Twickenham victory, in addition to two others under Gatland in 2008 and 2012, gives Wales a confidence that no other northern hemisphere visitor can bring to south west London.

Of his 77 caps, 43 have come as a replacement.

England coach Eddie Jones was forced into making at least one change after first-choice scrum-half Ben Youngs went off after just 10 minutes at Rome's Stadio Olimpico with a knee injury that has ended his involvement in the Six Nations.

The Bath centre is preferred to Worcester Warriors' Ben Te'o in England's starting XV and has been tasked with showcasing the fruits of his experience - particularly in defence.

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