5 takeaways from the Bills loss to the Saints

The Bills have two road games - at the Los Angeles Chargers and Kansas City Chiefs - before returning home in December to host the New England Patriots in a game that will likely mean more for the Bills' chances at a wild-card playoff berth than winning the division.

-New Orleans had little trouble responding with a nine-play scoring drive covering 75 yards.

Ingram found paydirt again in the second quarter with a 3-yard touchdown run.

Lasco raised a fist as he was wheeled to the ambulance. Overall, the Bills' defense allowed 298 rushing yards and 482 total yards to the Saints as they got blown out of their own stadium. One play later Mark Ingram was in the end zone for his third touchdown of the day, but the point after attempt failed (30-3) midway through the third quarter. Still, despite the lack of touchdown throws, Brees was fifth in the National Football League with 2,214 yards passing and was tied for eighth with 13 passing touchdowns. His second score of the contest, extended the Saints lead to 14-3. Wide receiver Kelvin Benjamin will make his Bills' debut.

-LeSean McCoy found running the ball hard again as he managed just 49 yards on eight carries.

There were physically dominated on the line of scrimmage from the first whistle as quarterback Tyrod Taylor took seven sacks under constant pressure as the game rapidly slipped from their grasp. He finished 7-10 for 79 yards and a touchdown. It was a season low in both conversions and conversion percentage for 2017.